The Space Marine Vindicator is a heavy support vehicle. During the uprising of Sabien IV, Imperial forces became embroiled in a bitter siege for the manufacturing citadel of Van Valdt. After several failed assaults, the deadlock was eventually broken with the aid of Vindicators from the Iron Hands Chapter who used the tank's renforced armor and powerful siege cannon to quite literally blast their way into the city. Working in small squadrons of three tanks, the Vindicators and supporting Tactical squads of the Iron Hands 7th company breached the rebel defences time and time again making space for the supporting Imperial infantry to secure each district. Within five days, the final bastions of rebel resistance had collapsed under the Vindicators' brutal fire bringing to an end a siege that had lasted over three months.

A Vindicator may be fielded in a Space Marine army as a Heavy Support unit choice.